rat FTSJD2 shRNA silencing AAV

Name
AAV-r-FTSJD2-shRNA

Cat No
shAAV-292187

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Cmtr1.

shAAV-292187

AAV-r-FTSJD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Cmtr1 (cap methyltransferase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ftsjd2; LRRG00129; MTr1; RGD1307801

Description (Vector)

S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.

Gene ID

309656

Gene Name (Vector)

cap methyltransferase 1

Gene Symbol

Cmtr1

ORF Size (aa)

2514

ORF Size (bp)

2514 bp

RefSeq ID

NM_001014031

RefSeq Synonyms

NM_001014031, BC085799,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.