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rat TRAF4AF1 shRNA silencing AAV

Name 
AAV-r-TRAF4AF1-shRNA
Cat No 
shAAV-292019
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Knstrn.

shAAV-292019
AAV-r-TRAF4AF1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Knstrn (kinetochore-localized astrin/SPAG5 binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C15orf23; SKAP; Traf4af1
Description (Vector)
Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Gene ID
311325
Gene Name (Vector)
kinetochore-localized astrin/SPAG5 binding protein
Gene Symbol
Knstrn
ORF Size (aa)
939
ORF Size (bp)
939 bp
RefSeq ID
NM_001004264
RefSeq Synonyms
NM_001004264, BC079438,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.