rat RDBP shRNA silencing AAV

Name
AAV-r-RDBP-shRNA

Cat No
shAAV-292011

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Nelfe.

shAAV-292011

AAV-r-RDBP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Nelfe (negative elongation factor complex member E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Rd; Rdbp

Description (Vector)

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex.

Gene ID

294258

Gene Name (Vector)

negative elongation factor complex member E

Gene Symbol

Nelfe

ORF Size (aa)

1110

ORF Size (bp)

1110 bp

RefSeq ID

NM_001165901

RefSeq Synonyms

NM_212548, NM_001165901, BC079427,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.