rat PPP2R2D shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Ppp2r2d.
shAAV-291503
AAV-r-PPP2R2D-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Ppp2r2d (protein phosphatase 2, regulatory subunit B, delta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
Gene ID
246255
Gene Name (Vector)
protein phosphatase 2, regulatory subunit B, delta
Gene Symbol
Ppp2r2d
ORF Size (aa)
1362
ORF Size (bp)
1362 bp
RefSeq ID
NM_144746
RefSeq Synonyms
NM_144746, BC081720,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.