human IGSF8 Over-expression AAV

Name
AAV-h-IGSF8

Cat No
AAV-212001

Availability
4-5 weeks

This is an AAV expressing Human IGSF8.

AAV-212001

AAV-h-IGSF8

Ready-to-use AAV expressing Human IGSF8 (immunoglobulin superfamily member 8). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CD316; CD81P3; EWI-2; EWI2; KCT-4; LIR-D1; PGRL

Description (Vector)

IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene ID

93185

Gene Name (Vector)

immunoglobulin superfamily member 8

Gene Symbol

IGSF8

HGNC ID

HGNC:17813

ORF Size (aa)

1842

ORF Size (bp)

1842 bp

RefSeq ID

NM_052868

RefSeq Synonyms

NM_052868, NM_001320247, NM_001206665, BC053881,

Species

human

UniGene ID

Hs.332012

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.