rat RNPS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Rnps1.
shAAV-291133
AAV-r-RNPS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Rnps1 (RNA binding protein S1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Part of pre- and post-splicing multiprotein mRNP complexes. Enhances the formation of the ATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 and TRA2B/SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner. Participates in mRNA 3'-end cleavage. Involved in UPF2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Also mediates increase of mRNA abundance and translational efficiency. Binds spliced mRNA 20-25 nt upstream of exon-exon junctions.
Gene ID
287113
Gene Name (Vector)
RNA binding protein S1
Gene Symbol
Rnps1
ORF Size (aa)
918
ORF Size (bp)
918 bp
RefSeq ID
NM_001011890
RefSeq Synonyms
NM_001011890, BC079014,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.