rat ADAMTS1 shRNA silencing AAV

Name
AAV-r-ADAMTS1-shRNA

Cat No
shAAV-291057

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Adamts1.

shAAV-291057

AAV-r-ADAMTS1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Adamts1 (ADAM metallopeptidase with thrombospondin type 1 motif, 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover (By similarity). Has angiogenic inhibitor activity. Active metalloprotease, which may be associated with various inflammatory processes as well as development of cancer cachexia. May play a critical role in follicular rupture.

Gene ID

79252

Gene Name (Vector)

ADAM metallopeptidase with thrombospondin type 1 motif, 1

Gene Symbol

Adamts1

ORF Size (aa)

2904

ORF Size (bp)

2904 bp

RefSeq ID

NM_024400

RefSeq Synonyms

NM_024400, BC080237,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.