human IGBP1 Over-expression AAV

Name 
AAV-h-IGBP1
Cat No 
AAV-211904
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IGBP1.

AAV-211904
AAV-h-IGBP1

Ready-to-use AAV expressing Human IGBP1 (immunoglobulin (CD79A) binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ALPHA-4; B cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); B-cell signal transduction molecule alpha 4; CD79a-binding protein 1; IBP1; immunoglobulin (CD79A) binding protein 1; immunoglobulin-binding protein 1; protein alpha-4; protein phosphatase 2/4/6 regulatory subunit; protein phosphatase 2A, regulatory subunit alpha-4; renal carcinoma antigen NY-REN-16
Description (eCommerce)
Alpha-4 is involved in the rapamycin sensitive mTOR pathway through its association with the PP2Ac phosphatase. Alpha-4 may regulate PP2Ac activity for the cell cycle progression of lymphocytes. Alpha-4 is also associated to surface IgM receptors and is involved in B-cell receptor mediated signal transduction.
Description (Vector)
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.
Gene ID
3476
Gene Name (eCommerce)
immunoglobulin binding protein 1
Gene Name (Vector)
immunoglobulin (CD79A) binding protein 1
Gene Symbol
IGBP1
HGNC ID
HGNC:5461
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1020
Protein Name (eCommerce)
Immunoglobulin-binding protein 1
RefSeq ID
NM_001551
RefSeq Synonyms
NM_001551, BC004137,
Research Areas
Apoptosis,Cancer,Immunology,Interleukin Signaling,MAPK Signaling,Neurobiology,Signal Transduction
Research Areas (Faceted)
cancer,cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
Alpha-4 is involved in the rapamycin sensitive mTOR pathway through its association with the PP2Ac phosphatase. Alpha-4 may regulate PP2Ac activity for the cell cycle progression of lymphocytes. Alpha-4 is also associated to surface IgM receptors and is involved in B-cell receptor mediated signal transduction.
UniGene ID
Hs.496267
UniProt ID (eCommerce)
P78318

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.