rat AKR1C21 shRNA silencing AAV

Name
AAV-r-AKR1C21-shRNA

Cat No
shAAV-291018

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Akr1c2.

shAAV-291018

AAV-r-AKR1C21-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Akr1c2 (aldo-keto reductase family 1, member C2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Akr1c21

Description (Vector)

Works in concert with the 5-alpha/5-beta-steroid reductases to convert steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-tetrahydrosteroids. Catalyzes the inactivation of the most potent androgen 5-alpha-dihydrotestosterone (5-alpha-DHT) to 5-alpha-androstane-3-alpha,17-beta-diol (3-alpha-diol). Has a high bile-binding ability.

Gene ID

291283

Gene Name (Vector)

aldo-keto reductase family 1, member C2

Gene Symbol

Akr1c2

ORF Size (aa)

957

RefSeq ID

NM_001013057

RefSeq Synonyms

NM_001013057, BC078957,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.