rat HSD11B1 shRNA silencing AAV

Name
AAV-r-HSD11B1-shRNA

Cat No
shAAV-290955

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Hsd11b1.

shAAV-290955

AAV-r-HSD11B1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Hsd11b1 (hydroxysteroid 11-beta dehydrogenase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LRRGT00065

Description (Vector)

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).

Gene ID

25116

Gene Name (Vector)

hydroxysteroid 11-beta dehydrogenase 1

Gene Symbol

Hsd11b1

ORF Size (aa)

867

ORF Size (bp)

867 bp

RefSeq ID

NM_017080

RefSeq Synonyms

NM_017080, BC078865,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.