rat SERPINA1 shRNA silencing AAV

Name
AAV-r-SERPINA1-shRNA

Cat No
shAAV-290832

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Serpina1.

shAAV-290832

AAV-r-SERPINA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Serpina1 (serpin family A member 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AAT; Pi; Spi1

Description (Vector)

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin|Function: Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Gene ID

24648

Gene Name (Vector)

serpin family A member 1

Gene Symbol

Serpina1

ORF Size (aa)

1236

ORF Size (bp)

1236 bp

RefSeq ID

NM_022519

RefSeq Synonyms

NM_022519, BC078824,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.