rat MMP14 shRNA silencing AAV

Name
AAV-r-MMP14-shRNA

Cat No
shAAV-290710

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Mmp14.

shAAV-290710

AAV-r-MMP14-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Mmp14 (matrix metallopeptidase 14). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Mt1-mmp

Description (Vector)

Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7.

Gene ID

81707

Gene Name (Vector)

matrix metallopeptidase 14

Gene Symbol

Mmp14

ORF Size (aa)

1749

ORF Size (bp)

1749 bp

RefSeq ID

NM_031056

RefSeq Synonyms

NM_031056, BC072509,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.