rat GNE shRNA silencing AAV

Name
AAV-r-GNE-shRNA

Cat No
shAAV-290569

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Gne.

shAAV-290569

AAV-r-GNE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Uae1

Description (Vector)

Regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.

Gene ID

114711

Gene Name (Vector)

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

Gene Symbol

Gne

ORF Size (aa)

2169

ORF Size (bp)

2169 bp

RefSeq ID

NM_053765

RefSeq Synonyms

NM_053765, BC062011,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.