rat SEMG1 shRNA silencing AAV

Name
AAV-r-SEMG1-shRNA

Cat No
shAAV-290537

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Semg1.

shAAV-290537

AAV-r-SEMG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Semg1 (semenogelin I). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RATSVPIIA; Svp1; SVPIIA; Svs2; SVS2P; Svs2p2

Description (Vector)

Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA|Function: Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.

Gene ID

25013

Gene Name (Vector)

semenogelin I

Gene Symbol

Semg1

ORF Size (aa)

1245

ORF Size (bp)

1245 bp

RefSeq ID

NM_012710

RefSeq Synonyms

NM_012710, BC061977,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.