rat GEFT shRNA silencing AAV

Name
AAV-r-GEFT-shRNA

Cat No
shAAV-290511

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Arhgef25.

shAAV-290511

AAV-r-GEFT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Arhgef25 (Rho guanine nucleotide exchange factor 25). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Geft

Description (Vector)

ARHGEF25 may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis (By similarity).

Gene ID

314904

Gene Name (Vector)

Rho guanine nucleotide exchange factor 25

Gene Symbol

Arhgef25

ORF Size (aa)

1740

ORF Size (bp)

1740 bp

RefSeq ID

NM_199395

RefSeq Synonyms

NM_199395, BC061879,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.