human ICA1 Over-expression AAV

Name 
AAV-h-ICA1
Cat No 
AAV-211745
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ICA1.

AAV-211745
AAV-h-ICA1

Ready-to-use AAV expressing Human ICA1 (islet cell autoantigen 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ICA69; ICAp69
Description (Vector)
ICA1 encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Gene ID
3382
Gene Name (Vector)
islet cell autoantigen 1
Gene Symbol
ICA1
HGNC ID
HGNC:5343
ORF Size (aa)
1449
ORF Size (bp)
1449 bp
RefSeq ID
NM_004968
RefSeq Synonyms
NM_022307, NM_004968, NM_001276478, NM_001136020, BC008640,
Species
human
UniGene ID
Hs.487561

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.