rat SELS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Selenos.
shAAV-290048
AAV-r-SELS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Selenos (selenoprotein S). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Sels; sg2; Vimp
Description (Vector)
Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
Gene ID
286900
Gene Name (Vector)
selenoprotein S
Gene Symbol
Selenos
ORF Size (aa)
567
RefSeq ID
NM_173120
RefSeq Synonyms
NM_173120, BC059111,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.