mouse POLK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Polk.
shAAV-280986
AAV-m-POLK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Polk (polymerase (DNA directed), kappa). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dinb1; DINP
Description (Vector)
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Gene ID
27015
Gene Name (Vector)
polymerase (DNA directed), kappa
Gene Symbol
Polk
ORF Size (aa)
2220
ORF Size (bp)
2220 bp
RefSeq ID
NM_012048
RefSeq Synonyms
NM_012048, NM_001347606, NM_001347604, NM_001347603, NM_001347602, BC052820,
Species
mouse
UniGene ID
Mm.89926
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.