mouse NLRX1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Nlrx1.
shAAV-280918
AAV-m-NLRX1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Nlrx1 (NLR family member X1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC034204; NOD9
Description (Vector)
Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
Gene ID
270151
Gene Name (Vector)
NLR family member X1
Gene Symbol
Nlrx1
ORF Size (aa)
2928
ORF Size (bp)
2928 bp
RefSeq ID
NM_178420
RefSeq Synonyms
NM_178420, NM_001163743, NM_001163742, BC050054,
Species
mouse
UniGene ID
Mm.3957
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.