human HTR2B Over-expression AAV

Name 
AAV-h-HTR2B
Cat No 
AAV-211694
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HTR2B.

AAV-211694
AAV-h-HTR2B

Ready-to-use AAV expressing Human HTR2B (5-hydroxytryptamine receptor 2B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5-HT(2B); 5-HT-2B; 5-HT2B
Description (Vector)
HTR2B encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.
Gene ID
3357
Gene Name (Vector)
5-hydroxytryptamine receptor 2B
Gene Symbol
HTR2B
HGNC ID
HGNC:5294
ORF Size (aa)
1446
ORF Size (bp)
1446 bp
RefSeq ID
NM_000867
RefSeq Synonyms
NM_001320758, NM_000867, BC063123,
Species
human
UniGene ID
Hs.421649

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.