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mouse FERMT3 shRNA silencing AAV

Name 
AAV-m-FERMT3-shRNA
Cat No 
shAAV-280750
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Fermt3.

shAAV-280750
AAV-m-FERMT3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Fermt3 (fermitin family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C79673; Kindlin3
Description (Vector)
Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (By similarity)|Function: Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.
Gene ID
108101
Gene Name (Vector)
fermitin family member 3
Gene Symbol
Fermt3
ORF Size (aa)
1593
ORF Size (bp)
1593 bp
RefSeq ID
NM_153795
RefSeq Synonyms
NM_153795, BC066803, BC032204, BC025119,
Species
mouse
UniGene ID
Mm.157591

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.