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mouse CHRDL1 shRNA silencing AAV

Name 
AAV-m-CHRDL1-shRNA
Cat No 
shAAV-280639
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Chrdl1.

shAAV-280639
AAV-m-CHRDL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Chrdl1 (chordin-like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CHL; CHL1; Nrln1; VOPT
Description (Vector)
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
Gene ID
83453
Gene Name (Vector)
chordin-like 1
Gene Symbol
Chrdl1
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_031258
RefSeq Synonyms
NM_031258, NM_001114385, BC066832,
Species
mouse
UniGene ID
Mm.477555

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.