mouse ABCG2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Abcg2.
shAAV-280528
AAV-m-ABCG2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Abcg2 (ATP-binding cassette, sub-family G (WHITE), member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ABC15; ABCP; AI428558; BCRP; Bcrp1; MXR; MXR1
Description (Vector)
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
Gene ID
26357
Gene Name (Vector)
ATP-binding cassette, sub-family G (WHITE), member 2
Gene Symbol
Abcg2
ORF Size (aa)
1974
ORF Size (bp)
1974 bp
RefSeq ID
NM_011920
RefSeq Synonyms
NM_011920, BC053730,
Species
mouse
UniGene ID
Mm.333096
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.