mouse LZTS2 shRNA silencing AAV

Name 
AAV-m-LZTS2-shRNA
Cat No 
shAAV-280310
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Lzts2.

shAAV-280310
AAV-m-LZTS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lzts2 (leucine zipper, putative tumor suppressor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BC014695; LAPSER1; mKIAA1813
Description (Vector)
Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.
Gene ID
226154
Gene Name (Vector)
leucine zipper, putative tumor suppressor 2
Gene Symbol
Lzts2
ORF Size (aa)
2016
ORF Size (bp)
2016 bp
RefSeq ID
NM_145503
RefSeq Synonyms
NM_145503, NM_001130526, NM_001130525, BC092263, BC014695,
Species
mouse
UniGene ID
Mm.28204

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.