mouse ACSL3 shRNA silencing AAV

Name
AAV-m-ACSL3-shRNA

Cat No
shAAV-279408

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Acsl3.

shAAV-279408

AAV-m-ACSL3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Acsl3 (acyl-CoA synthetase long-chain family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

2610510B12Rik; Acs3; C85929; Facl3; Pro2194

Description (Vector)

Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins).

Gene ID

74205

Gene Name (Vector)

acyl-CoA synthetase long-chain family member 3

Gene Symbol

Acsl3

ORF Size (aa)

2163

ORF Size (bp)

2163 bp

RefSeq ID

NM_028817

RefSeq Synonyms

NM_028817, NM_001136222, NM_001033606, BC031529,

Species

mouse

UniGene ID

Mm.

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.