mouse MUC20 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Muc20.
shAAV-279284
AAV-m-MUC20-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Muc20 (mucin 20). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BC026367
Description (Vector)
MUC20 may regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Gene ID
224116
Gene Name (Vector)
mucin 20
Gene Symbol
Muc20
ORF Size (aa)
1851
ORF Size (bp)
1851 bp
RefSeq ID
NM_146071
RefSeq Synonyms
NM_146071, NM_001145874, BC026367,
Species
mouse
UniGene ID
Mm.153301
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.