mouse ANG shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ang.
shAAV-278866
AAV-m-ANG-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ang (angiogenin, ribonuclease, RNase A family, 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI385586; Ang1; Rnase5; Rnase5a
Description (Vector)
ANG may function as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.
Gene ID
11727
Gene Name (Vector)
angiogenin, ribonuclease, RNase A family, 5
Gene Symbol
Ang
ORF Size (aa)
438
ORF Size (bp)
438 bp
RefSeq ID
NM_007447
RefSeq Synonyms
NM_007447, NM_001161731, BC055355,
Species
mouse
UniGene ID
Mm.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.