mouse API5 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Api5.
shAAV-278554
AAV-m-API5-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Api5 (apoptosis inhibitor 5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AAC-11; AI196452; API-5
Description (Vector)
Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs.
Gene ID
11800
Gene Name (Vector)
apoptosis inhibitor 5
Gene Symbol
Api5
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_007466
RefSeq Synonyms
NM_007466, NM_001305258, BC007133,
Species
mouse
UniGene ID
Mm.181824
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.