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human HSD17B8 Over-expression AAV

Name 
AAV-h-HSD17B8
Cat No 
AAV-211582
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HSD17B8.

AAV-211582
AAV-h-HSD17B8

Ready-to-use AAV expressing Human HSD17B8 (hydroxysteroid 17-beta dehydrogenase 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1
Description (Vector)
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
Gene ID
7923
Gene Name (Vector)
hydroxysteroid 17-beta dehydrogenase 8
Gene Symbol
HSD17B8
HGNC ID
HGNC:3554
ORF Size (aa)
786
ORF Size (bp)
786 bp
RefSeq ID
NM_014234
RefSeq Synonyms
NM_014234, BC008185,
Species
human
UniGene ID
Hs.415058

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.