mouse ZFYVE9 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Zfyve9.
shAAV-277054
AAV-m-ZFYVE9-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Zfyve9 (zinc finger, FYVE domain containing 9). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Madhip; NSP; SARA; SMADIP
Description (Vector)
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.
Gene ID
230597
Gene Name (Vector)
zinc finger, FYVE domain containing 9
Gene Symbol
Zfyve9
ORF Size (aa)
2121
ORF Size (bp)
2121 bp
RefSeq ID
NM_183300
RefSeq Synonyms
NM_183300, NM_001347163, BC172690, BC156514,
Species
mouse
UniGene ID
Mm.196776
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.