human HPR Over-expression AAV

Name 
AAV-h-HPR
Cat No 
AAV-211500
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HPR.

AAV-211500
AAV-h-HPR

Ready-to-use AAV expressing Human HPR (haptoglobin-related protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
A-259H10.2; HP
Description (Vector)
HPR encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.
Gene ID
3250
Gene Name (Vector)
haptoglobin-related protein
Gene Symbol
HPR
HGNC ID
HGNC:5156
ORF Size (aa)
1047
ORF Size (bp)
1047 bp
RefSeq ID
NM_020995
RefSeq Synonyms
NM_020995, BC160066,
Species
human
UniGene ID
Hs.655361

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.