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mouse WDR68 shRNA silencing AAV

Name 
AAV-m-WDR68-shRNA
Cat No 
shAAV-276227
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Dcaf7.

shAAV-276227
AAV-m-WDR68-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Dcaf7 (DDB1 and CUL4 associated factor 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1700012F10Rik; 2610037L01Rik; C86529; HAN11; Wdr68
Description (Vector)
Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Gene ID
71833
Gene Name (Vector)
DDB1 and CUL4 associated factor 7
Gene Symbol
Dcaf7
ORF Size (aa)
1029
ORF Size (bp)
1029 bp
RefSeq ID
NM_027946
RefSeq Synonyms
NM_027946, BC048722, BC048165,
Species
mouse
UniGene ID
Mm.307455

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.