mouse VAX2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Vax2.
shAAV-275978
AAV-m-VAX2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Vax2 (ventral anterior homeobox 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Dres93
Description (Vector)
Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity). May be a regulator of axial polarization in the retina.
Gene ID
24113
Gene Name (Vector)
ventral anterior homeobox 2
Gene Symbol
Vax2
ORF Size (aa)
879
RefSeq ID
NM_011912
RefSeq Synonyms
NM_011912, BC116390, BC116389, BC090635,
Species
mouse
UniGene ID
Mm.307165
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.