mouse UNC93B1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Unc93b1.
shAAV-275649
AAV-m-UNC93B1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Unc93b1 (unc-93 homolog B1 (C. elegans)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Unc-93B1; Unc93b
Description (Vector)
Plays an important role in innate and adaptive immunity by regulating nucleotide-sensing Toll-like receptor (TLR) signaling. Required for the transport of a subset of TLRs (including TLR3, TLR7 and TLR9) from the endoplasmic reticulum to endolysosomes where they can engage pathogen nucleotides and activate signaling cascades. May play a role in autoreactive B-cells removal.
Gene ID
54445
Gene Name (Vector)
unc-93 homolog B1 (C. elegans)
Gene Symbol
Unc93b1
ORF Size (aa)
1797
ORF Size (bp)
1797 bp
RefSeq ID
NM_019449
RefSeq Synonyms
NM_019449, NM_001161428, BC023731, BC018388,
Species
mouse
UniGene ID
Mm.262094
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.