mouse UBXN1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ubxn1.
shAAV-275550
AAV-m-UBXN1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ubxn1 (UBX domain protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2B28; 4930455J02Rik; D19Ertd721e; T25529
Description (Vector)
Ubiquitin-binding protein that interacts with the BRCA1-BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.
Gene ID
225896
Gene Name (Vector)
UBX domain protein 1
Gene Symbol
Ubxn1
ORF Size (aa)
894
RefSeq ID
NM_146093
RefSeq Synonyms
NM_146093, BC006701,
Species
mouse
UniGene ID
Mm.27839
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.