mouse UBE2D1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Ube2d1.
shAAV-275467
AAV-m-UBE2D1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Ube2d1 (ubiquitin-conjugating enzyme E2D 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
UBCH5
Description (Vector)
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1. Ubiquitinates STUB1-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
Gene ID
216080
Gene Name (Vector)
ubiquitin-conjugating enzyme E2D 1
Gene Symbol
Ube2d1
ORF Size (aa)
444
ORF Size (bp)
444 bp
RefSeq ID
NM_145420
RefSeq Synonyms
NM_145420, BC019464,
Species
mouse
UniGene ID
Mm.270530
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.