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mouse TXNDC3 shRNA silencing AAV

Name 
AAV-m-TXNDC3-shRNA
Cat No 
shAAV-275388
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Nme8.

shAAV-275388
AAV-m-TXNDC3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Nme8 (NME/NM23 family member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1700056P15Rik; Sptrx-2; Txndc3
Description (Vector)
Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds.
Gene ID
73412
Gene Name (Vector)
NME/NM23 family member 8
Gene Symbol
Nme8
ORF Size (aa)
1413
ORF Size (bp)
1413 bp
RefSeq ID
NM_181591
RefSeq Synonyms
NM_181591, NM_001167909, BC052356,
Species
mouse
UniGene ID
Mm.279939

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.