mouse TXNDC2 shRNA silencing AAV

Name 
AAV-m-TXNDC2-shRNA
Cat No 
shAAV-275387
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Txndc2.

shAAV-275387
AAV-m-TXNDC2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Txndc2 (thioredoxin domain containing 2 (spermatozoa)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AU021712; Sptrx-1; Sptrx1; Trx4
Description (Vector)
Probably plays a regulatory role in sperm development. May participate in regulation of fibrous sheath (FS) assembly by supporting the formation of disulfide bonds during sperm tail morphogenesis. May also be required to rectify incorrect disulfide pairing and generate suitable pairs between the FS constituents. Can reduce disulfide bonds in vitro in the presence of NADP and thioredoxin reductase.
Gene ID
213272
Gene Name (Vector)
thioredoxin domain containing 2 (spermatozoa)
Gene Symbol
Txndc2
ORF Size (aa)
1548
ORF Size (bp)
1548 bp
RefSeq ID
NM_153519
RefSeq Synonyms
NM_153519, NM_001146002, BC060981,
Species
mouse
UniGene ID
Mm.255732

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.