mouse TSEPA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Themis.
shAAV-275134
AAV-m-TSEPA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Themis (thymocyte selection associated). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
E430004N04Rik; Gasp; Spot; thylex; Tsepa
Description (Vector)
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk (By similarity).
Gene ID
210757
Gene Name (Vector)
thymocyte selection associated
Gene Symbol
Themis
ORF Size (aa)
1911
ORF Size (bp)
1911 bp
RefSeq ID
NM_178666
RefSeq Synonyms
NM_178666, NM_001305663, BC125488, BC125486,
Species
mouse
UniGene ID
Mm.123021
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.