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mouse TRPV3 shRNA silencing AAV

Name 
AAV-m-TRPV3-shRNA
Cat No 
shAAV-275108
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Trpv3.

shAAV-275108
AAV-m-TRPV3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Trpv3 (transient receptor potential cation channel, subfamily V, member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
1110036I10Rik; AI644701; Nh; VRL3
Description (Vector)
Putative receptor-activated non-selective calcium permeant cation channel. It is activated by innocuous (warm) temperatures and shows an increased response at noxious temperatures greater than 39 degrees Celsius. Activation exhibits an outward rectification. May associate with TRPV1 and may modulate its activity. Is a negative regulator of hair growth and cycling: TRPV3-coupled signaling suppresses keratinocyte proliferation in hair follicles and induces apoptosis and premature hair follicle regression (catagen).
Gene ID
246788
Gene Name (Vector)
transient receptor potential cation channel, subfamily V, member 3
Gene Symbol
Trpv3
ORF Size (aa)
2373
ORF Size (bp)
2373 bp
RefSeq ID
NM_145099
RefSeq Synonyms
NM_145099, BC108984,
Species
mouse
UniGene ID
Mm.347652

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.