mouse TRIM56 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Trim56.
shAAV-275010
AAV-m-TRIM56-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Trim56 (tripartite motif-containing 56). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A130009K11Rik; Gm452; RNF109
Description (Vector)
E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA (By similarity).
Gene ID
384309
Gene Name (Vector)
tripartite motif-containing 56
Gene Symbol
Trim56
ORF Size (aa)
2205
ORF Size (bp)
2205 bp
RefSeq ID
NM_201373
RefSeq Synonyms
NM_201373, BC045615,
Species
mouse
UniGene ID
Mm.100647
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.