mouse TRIM27 shRNA silencing AAV

Name
AAV-m-TRIM27-shRNA

Cat No
shAAV-274979

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Trim27.

shAAV-274979

AAV-m-TRIM27-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Trim27 (tripartite motif-containing 27). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AW538890; Gm19403; Rfp

Description (Vector)

Has a transcriptional repressor activity by cooperating with EPC1. Induces apoptosis by activating Jun N-terminal kinase and p38 kinase and also increases caspase-3-like activity independently of mitochondrial events. May function in male germ cell development. Has DNA-binding activity and preferentially bound to double-stranded DNA (By similarity). E3 ubiquitin-protein ligase that mediates ubiquitination of PIK3C2B and inhibits its activity; mediates the formation of 'Lys-48'-linked polyubiquitin chains; the function inhibits CD4 T-cell activation.

Gene ID

19720

Gene Name (Vector)

tripartite motif-containing 27

Gene Symbol

Trim27

ORF Size (aa)

1542

ORF Size (bp)

1542 bp

RefSeq ID

NM_009054

RefSeq Synonyms

NM_009054, BC003219,

Species

mouse

UniGene ID

Mm.314056

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.