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mouse TPX2 shRNA silencing AAV

Name 
AAV-m-TPX2-shRNA
Cat No 
shAAV-274880
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tpx2.

shAAV-274880
AAV-m-TPX2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tpx2 (TPX2, microtubule-associated). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2610005B21Rik; DIL2; p100; REPP86
Description (Vector)
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
Gene ID
72119
Gene Name (Vector)
TPX2, microtubule-associated
Gene Symbol
Tpx2
ORF Size (aa)
2238
ORF Size (bp)
2238 bp
RefSeq ID
NM_028109
RefSeq Synonyms
NM_028109, NM_001141978, NM_001141977, NM_001141976, NM_001141975, BC060619,
Species
mouse
UniGene ID
Mm.407737

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.