mouse TPM1 shRNA silencing AAV

Name
AAV-m-TPM1-shRNA

Cat No
shAAV-274850

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Mouse Tpm1.

shAAV-274850

AAV-m-TPM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tpm1 (tropomyosin 1, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AA986836; AI854628; alpha-TM; TM2; Tm3; Tmpa; Tpm-1

Description (Vector)

Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.

Gene ID

22003

Gene Name (Vector)

tropomyosin 1, alpha

Gene Symbol

Tpm1

ORF Size (aa)

855

ORF Size (bp)

855 bp

RefSeq ID

NM_024427

RefSeq Synonyms

NM_024427, NM_001164256, NM_001164255, NM_001164254, NM_001164253, NM_001164252, NM_001164251, NM_001164250, NM_001164249, NM_001164248, BC145307, BC132037, BC132035,

Species

mouse

UniGene ID

Mm.121878

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.