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mouse TOX3 shRNA silencing AAV

Name 
AAV-m-TOX3-shRNA
Cat No 
shAAV-274830
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tox3.

shAAV-274830
AAV-m-TOX3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tox3 (TOX high mobility group box family member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
500-9; BC052044; C230068E13; CAGF9; Tnrc9
Description (Vector)
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.
Gene ID
244579
Gene Name (Vector)
TOX high mobility group box family member 3
Gene Symbol
Tox3
ORF Size (aa)
1728
ORF Size (bp)
1728 bp
RefSeq ID
NM_172913
RefSeq Synonyms
NM_172913, BC052044,
Species
mouse
UniGene ID
Mm.302755

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.