human HMOX2 Over-expression AAV

Name 
AAV-h-HMOX2
Cat No 
AAV-211315
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HMOX2.

AAV-211315
AAV-h-HMOX2

Ready-to-use AAV expressing Human HMOX2 (heme oxygenase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
heme oxygenase (decycling) 2; heme oxygenase 2; HO-2
Description (eCommerce)
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances [taken from NCBI Entrez Gene (Gene ID: 3163)].
Description (Vector)
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus.
Gene ID
3163
Gene Name (eCommerce)
heme oxygenase 2
Gene Name (Vector)
heme oxygenase 2
Gene Symbol
HMOX2
HGNC ID
HGNC:5014
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
951
ORF Size (bp)
951 bp
Protein Name (eCommerce)
Heme oxygenase 2
RefSeq ID
NM_002134
RefSeq Synonyms
NM_002134, NM_001286271, NM_001286270, NM_001286269, NM_001286268, NM_001286267, NM_001127206, NM_001127205, NM_001127204, BC002396,
Research Areas
Hypoxia,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances [taken from NCBI Entrez Gene (Gene ID: 3163)].
UniGene ID
Hs.284279
UniProt ID (eCommerce)
P30519

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.