mouse TIMP3 shRNA silencing AAV

Name 
AAV-m-TIMP3-shRNA
Cat No 
shAAV-274233
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Timp3.

shAAV-274233
AAV-m-TIMP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Timp3 (tissue inhibitor of metalloproteinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Timp-3
Description (Vector)
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Gene ID
21859
Gene Name (Vector)
tissue inhibitor of metalloproteinase 3
Gene Symbol
Timp3
ORF Size (aa)
636
ORF Size (bp)
636 bp
RefSeq ID
NM_011595
RefSeq Synonyms
NM_011595, BC014713,
Species
mouse
UniGene ID
Mm.4871

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.