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mouse TIMM50 shRNA silencing AAV

Name 
AAV-m-TIMM50-shRNA
Cat No 
shAAV-274223
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Timm50.

shAAV-274223
AAV-m-TIMM50-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Timm50 (translocase of inner mitochondrial membrane 50). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2810403L02Rik; AU015082; TIM50L
Description (Vector)
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Has some phosphatase activity in vitro; however such activity may not be relevant in vivo. Isoform 2 may participate in the release of snRNPs and SMN from the Cajal body.
Gene ID
66525
Gene Name (Vector)
translocase of inner mitochondrial membrane 50
Gene Symbol
Timm50
ORF Size (aa)
690
ORF Size (bp)
690 bp
RefSeq ID
NM_025616
RefSeq Synonyms
NM_025616, BC010303,
Species
mouse
UniGene ID
Mm.167913

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.