mouse TGM3 shRNA silencing AAV

Name 
AAV-m-TGM3-shRNA
Cat No 
shAAV-274119
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tgm3.

shAAV-274119
AAV-m-TGM3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tgm3 (transglutaminase 3, E polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AI893889; TG E; TG(E); TGase E; TGase-3; TGE; we
Description (Vector)
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity). In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Gene ID
21818
Gene Name (Vector)
transglutaminase 3, E polypeptide
Gene Symbol
Tgm3
ORF Size (aa)
2082
ORF Size (bp)
2082 bp
RefSeq ID
NM_009374
RefSeq Synonyms
NM_009374, BC129891, BC129890,
Species
mouse
UniGene ID
Mm.2961

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.