mouse TGFB1I1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse TGFB1I1.
shAAV-274100
AAV-m-TGFB1I1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse TGFB1I1 (transforming growth factor beta 1 induced transcript 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ARA55; hic-5; Hic5; TSC-5;
Description (Vector)
Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.
Gene ID
21804
Gene Name (Vector)
transforming growth factor beta 1 induced transcript 1
Gene Symbol
TGFB1I1
ORF Size (aa)
1335
ORF Size (bp)
1335 bp
RefSeq ID
NM_009365
RefSeq Synonyms
NM_009365, NM_001289553, NM_001289552, NM_001289551, NM_001289550, BC056362, BC002049,
Species
mouse
UniGene ID
Mm.3248
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.